In celebration of SSE’s 75th anniversary in 2021, Evolution [1] will be accepting and publishing monthly Perspectives throughout the year to highlight the major scientific contributions published in Evolution since its inception and their continuing influence on the field. If you are interested in contributing a Perspective on an Evolution paper that has significantly shaped your work, please first express your interest by emailing Evolution EiC Tracey Chapman at Tracey.Chapman@uea.ac.uk. Prospective articles will then be submitted using the usual online submission process [2], with a lead in time of approximately two months. We look forward to reading the accepted pieces and celebrating SSE’s achievements over three-quarters of a century!